中西药预防人工髋关节术后深静脉血栓形成的效果研究

目的 分析中西药预防人工髋关节术后深静脉血栓形成的临床效果。方法 收集2011年1月～2013年6月本院收治的人工髋关节术患者，遵循随机原则，将患者分为Ⅰ组与Ⅱ组，每组各60例。Ⅰ组在基础预防上加中药血栓通注射液预防深静脉血栓，Ⅱ组加西药低分子肝素钠针剂预防治疗，分析两组患者的临床预防效果。结果 两组患者DVT发病率差异无统计学意义（P〉0．05）。两组患者术后出血量、术后引流量及切开血肿、延迟愈合等并发症，差异有统计学意义（P〈0．05）。两组患者术前APTT差异无统计学意义（P〉0．05）。术后1、2周，两组患者APTT差异有统计学意义（P〈0．05）。术前及术后1、2周，两组患者PT、INR及PLT等凝血指标，差异无统计学意义（P〉0．05）。结论 采取中药血栓通与西药低分子肝素钠预防人工髋关节术后深静脉血栓形成．其有效性相似．可降低深静脉血栓发生率，且术后出血风险及切口并发症发生率较低分子钠组明显低，安全性高，故采取中药血栓通预防人工髋关节术后深静脉血栓形安全有效。

Effect study of Chinese and western medicine used in prevention of deep vein thrombosis after artificial hip joint surgery

Objective To analyze the clinical effects of Chinese and western medicine in the prevention of deep vein thrombosis after artificial hip joint surgery. Methods The patients who received artificial hip joint surgery in our hospital from January 2011 to June 2013 were collected.The patients were divided into group Ⅰ and group Ⅱ according to the random principle,with 60 patients in each group.Group Ⅰ used Chinese medicine Xueshuantong injection on the basis of basic prevention to prevent deep vein thrombosis and group Ⅱ received western medicine low molecular weight heparin sodium injection on the basis of basic prevention to prevent deep vein thrombosis.The clinical preventative effects of the two groups were analyzed. Results The two groups were not significantly different in the DVT incidence,with no statistical significance （P〉0.05）.The two groups were significantly different in the complications such as postoperative blood loss,postoperative drainage amount,incision hematoma and delayed healing,with statistical significance （P〈0.05）.The two groups were not significantly different in coagulation indicators such as PT,INR and PLT before surgery,1 week after surgery and 2 weeks after surgery,with no statistical significance （P〉0.05）. Conclusion Chinese medicine Xueshuantong and Western medicine low molecular heparin sodium have similar effectiveness in the prevention of deep vein thrombosis after artificial hip joint surgery and can reduce the incidence of deep vein thrombosis. Compared to low molecular sodium,Xeshuantong has significantly lower postoperative bleeding risk and incidence of incision complications and higher safety,thus Chinese medicine Xueshuantong is an effective method for preventing deep vein thrombosis after artificial hip joint surgery.