| 酸枣仁茶改善小鼠睡眠作用的研究 |
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| 引用本文： | 韩彦彬,姚思宇,赵鹏,李彬,张洁宏,黄超培,李凤文,梁坚,傅伟忠,王彦武.酸枣仁茶改善小鼠睡眠作用的研究[J].中国热带医学,2009,9(9):1947-1948. |
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| 作者姓名： | 韩彦彬 姚思宇 赵鹏 李彬 张洁宏 黄超培 李凤文 梁坚 傅伟忠 王彦武 |
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| 作者单位： | 广西壮族自治区疾病预防控制中心,广西,南宁,530028 |
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| 摘 要： | 目的研究酸枣仁茶改善小鼠睡眠作用的影响。方法分别以334、667、1334mg／kgBW剂量的酸枣仁茶给小鼠连续灌胃30d后，通过直接睡眠实验、延长戊巴比妥钠睡眠时间实验、巴比妥钠闽下剂量催眠实验和巴比妥钠睡眠潜伏期实验，观察不同剂量酸枣仁茶对小鼠睡眠的影响。结果酸枣仁茶能显著延长戊巴比妥钠睡眠时间（P〈0．01）、且睡眠发生率明显增加（P〈0．05）、缩短巴比妥钠睡眠潜伏期（P〈0．01），且无直接催眠作用，对小鼠的体重无明显影响。结论该酸枣仁茶具有改善小鼠睡眠的作用。
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| 关 键 词： | 酸枣仁 睡眠 小鼠 |
Effect of Semen Ciziphi Spinosae tea on sleeping quality of mice |
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| Institution: | HAN Yan-bin,YAOo Si-yu,ZHAO Peng,et al. ( Guangxi Zhuang Autonomous Regional Center for Disease Control and Prevention, Nanning 530028, Guangxi, P. R. China) |
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| Abstract: | Objective To investigate the effect of Semen Ziziphi Spinosae Tea on the sleep of mice. Methods Semen Zizipbi Spinosae Tea was consecutively orally given to mice with the doses of 334,667,1334 mg/ kg of body weight for 30 days. The effects of sleep improvement of the three dosages of Semen Ziziphi Spinosae Tea were observed. Results The sleep time of mice was prolonged obviously（P〈0.01 ） , the sleeping rate of mice was increased obviously（P〈0.05 ） , the sleep incubation period was decreased significantly （P〈0.01） ,and there no indirect sleep-inducing effect was observed . Conclusion Semen Ziziphi Spinosae Tea can improve the sleeping quality of the mice. |
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| Keywords: | Sleep improvement Semen Ziziphi Spinosae Tea Mice |
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