不同中医证型视神经脊髓炎患者临床特点比较

目的：探讨肝肾阴虚型与非肝肾阴虚型视神经脊髓炎（neuromyelitisoptica,NMO）患者临床特点差异。方法回顾性分析73例NMO患者的中医证型及临床特点,并根据中医证型的不同将其分为肝肾阴虚组和非肝肾阴虚组。将两组性别比例、发病年龄、年复发率等进行分析比较。结果肝肾阴虚组NMO患者49例,非肝肾阴虚组24例。肝肾阴虚组患者均兼夹痰热瘀,非肝肾阴虚组证型以气虚、气血亏虚、痰瘀为主。与非肝肾阴虚组相比,肝肾阴虚组患者女性多,年复发率较高（P〈0．05）,首次发病累及视力或视力、脊髓同时受累者居多（P〈0．05）。结论不同中医证型NMO患者临床特点存在一定差异。

Comparison of clinical features of Neuromyelitis Optica patients with different TCM syndrome types

Objective To investigate the differences of clinical features in patients with Neuromy-elitis Optica （ NMO） between liver-kidney yin deficiency type and non liver-kidney yin deficiency type. Methods TCM syndrome types and clinical features of 73 patients with NMO were analyzed retrospective-ly. According to the TCM syndrome types, patients were divided into two groups：liver-kidney yin deficien-cy（LKYD） group and non-liver-kidney yin deficiency （NLKYD） group. Sex ratio, age of onset and the annual relapse rate of two groups were compared. Results There were 49 cases in LKYD group, and 24 cases in NLKYD group. The liver-kidney yin deficiency patients are always combined with phlegm, heat and blood stasis syndromes. In LKYD group, the key syndromes were qi deficiency, blood deficiency, phlegm and blood stasis. Compared with NLKYD patients, there were more female, higher annualized re-lapse rate （P〈0. 05）, and more invasion of vision or vision combining with spinal cord of the first onset （P〈0. 05） in LKYD patients. Conclusion Different clinical features exit in NMO patients with different TCM syndrome types.