神经系统重大疾病中蛋白质组学的应用

神经系统疾病的发生是包括遗传、环境和自身免疫等多种因素综合作用的结果;患者的临床表现为多样性、病程进展多变性。因此,要阐明发病机制和进行有效治疗十分困难。蛋白质组学研究最显著的特点是能对生理与病理状态下的体液、组织或细胞中蛋白质组分进行大通量的综合分析,这无疑有助于对复杂多变的神经系统疾病进行较为全面的认识。

Proteomic Application in Nervous System Major Diseases

Nervous system diseases are considered to be resulted from multitude factors,including inherit,environment,autoimmune and so forth.It is much difficult to elucidate their etiopathogenesis and to acquire a good curative effect,because of most of the patients having varied clinical symptoms and variable progression.For the proteomic technology,a predominant potentiality is able to obtain high-throughout proteome mapping from humor,tissue or cell,which is benefit to recognize complex and varied nervous system diseases by comparing the differences of protein expressions between physiological and pathological states.