The relationship between the presence of anti-cyclic citrullinated peptide antibodies and clinical phenotype in very early rheumatoid arthritis |
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| Authors: | Mohammed Z Cader Andrew D Filer Christopher D Buckley Karim Raza |
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| Affiliation: | (1) MRC Centre for Immune Regulation, School of Immunity and Infection, The University of Birmingham, Birmingham, B15 2TT, UK;(2) Department of Rheumatology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, B18 7QH, UK |
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| Abstract: | Background Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific for RA, but are not detectable in all RA patients. The aim of this study was to establish whether the clinical phenotypes of anti-CCP positive and negative disease are distinct at the earliest clinically apparent phase of disease. |
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