| MOCA对大鼠红细胞膜流动性的影响 |
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| 引用本文： | 徐晓莹,张永杰.MOCA对大鼠红细胞膜流动性的影响[J].哈尔滨医科大学学报,1998,32(6):428-429. |
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| 作者姓名： | 徐晓莹 张永杰 |
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| 作者单位： | [1]哈尔滨医科大学生化教研室 [2]哈尔滨医科大学二院眼科 |
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| 摘 要： | 采用荧光偏振法，以ＤＰＨ为探针，测定了红细胞膜的流动性，实验结果表明，４，４′－亚甲基双（α－氯苯胺）（ＭＯＣＡ）可引起红细胞膜损伤，导致膜流动性降低，而加入ＶＣ或ＶＥ后，均可使膜流动性恢复近于正常水平，提示ＶＣ和ＶＥ可保护红细胞，免于ＭＯＣＡ的损伤作用。
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| 关 键 词： | 氯苯胺 膜流动性 红细胞 维生素E 维生素C MOCA |
Effect of MOCA in Erythrocyte Membrane Fluidity of Rat |
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| Xu Xiaoying et al.Effect of MOCA in Erythrocyte Membrane Fluidity of Rat[J].Journal of Harbin Medical University,1998,32(6):428-429. |
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| Authors: | Xu Xiaoying |
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| Institution: | Department of Biochemistry |
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| Abstract: | The fluidity of erythrocyte membrane in rat was determined using the method of fluorescence polarization with DPH as probe.The results showed that MOCA could cause the damage of erythrocyte membrane and lead to the reduction of membrane fluidity.The membrane fluidity reached normal level when vitamine C or vitamine E was added.This demonstrated that vitamine C or vitamine E can protect erythrocyte membrane from the damage caused by MOCA. |
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| Keywords: | MOCA Membrane fluidity Erythrocyte Vitamin C Vitamin E |
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