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Bilateral blepharochalasis
Authors:A Dó  zsa&dagger  ,ZS Ká  rolyi&dagger  ,P Degrell&Dagger  
Affiliation:Department of Dermatology Semmelweis Hospital, Miskolc, Hungary. adozsa@indi.biochem.dote.hu
Abstract:Blepharochalasis is a rare disorder characterized by recurrent painless periorbital oedema, which leads to atrophy of the periorbital skin. Pathomechanism of the disease is probably immunological with a nearly complete loss of elastic fibres. The authors describe a 17-year-old woman, who was followed for 7 years. IgA deposits were found in the periorbital tissues, which confirm the immunological background of the condition. Electron microscopy results show that not only elastic but also collagen fibres were affected.
Keywords:bilateral blepharochalasis    collagen degradation    collagen fibres    cutis laxa    elastic fibres    fibronectin    IgA deposits    periorbital oedema
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