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微囊藻毒素污染及其促肝癌作用研究进展
引用本文:柳丽丽,钟儒刚,曾毅. 微囊藻毒素污染及其促肝癌作用研究进展[J]. 卫生研究, 2006, 35(3): 377-379
作者姓名:柳丽丽  钟儒刚  曾毅
作者单位:1. 北京工业大学生命科学与生物工程学院,北京,100022
2. 中国疾病预防控制中心病毒病预防控制所
摘    要:淡水水体的富营养化导致了蓝藻水华的普遍发生,微囊藻毒素是由蓝藻的部分藻属产生的环肽化合物,具有毒性大、分布广、结构稳定等特性,从而成为水环境中的重要潜在危害物质。微囊藻毒素已被证明具有明显的肝毒性,是肝肿瘤的促进剂之一。本文就微囊藻毒素的污染现状、肝毒性作用及其促肝癌机制等方面的研究进展进行了综述。

关 键 词:微囊藻毒素  肝毒性  肝癌  促癌作用
文章编号:1000-8020(2006)03-0377-03
收稿时间:2005-12-12
修稿时间:2005-12-12

Study progress on pollution and liver cancer promotion of microcystins
Liu Li-li,Zhong Ru-gang,Zeng Yi. Study progress on pollution and liver cancer promotion of microcystins[J]. Journal of hygiene research, 2006, 35(3): 377-379
Authors:Liu Li-li  Zhong Ru-gang  Zeng Yi
Affiliation:College of Life Sciences and Bioengineering, Beijing University of Technology, Beijing 100022, China
Abstract:Eutrophication of fresh water lakes and ponds has caused the occurrence of cyanobacteria. Microcystins(MCs)is a class of toxic cyclic heptapeptide, which may be produced by some strains of various blue-green algae. It has become potential hazardous material in aquatic environments for its toxic, distribution and stability. MCs has been showed to be extremely potent hepatotoxins and been viewed as a promoter of liver tumor. In this review, the pollution condition of MCs and its hepatotoxins as well as its mechanisms have been summarized.
Keywords:microcystins   hepatotoxin   liver tumor   tumor promotion
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