超声定量检测对乙肝患者肝纤维化的评估价值

目的分析超声定量检测对乙肝患者肝纤维化程度的评估价值。方法选取160例慢性乙肝患者作为临床研究对象，所有患者均接受超声定量检测和肝组织活检，对照研究不同病理分期患者的肝包膜厚度，脾脏长径、厚度，脾门静脉内径，门静脉主干内径以及胆囊壁厚度，并评价超声定量检测对患者肝纤维化的诊断准确性。结果S0-S2期肝纤维化患者各检测指标呈上升趋势，但组间比较差异无统计学意义（P〉0．05）；S3、S4期患者各检测指标均屁著高于S0、S1期患者，差异有统计学意义（P〈0．01）。超声定量检测对轻、中度肝纤维化及早期肝硬化的准确性分别为92％、97％和82％。结论超声定量检测具有无创性、可重复性等优势，且对乙肝患者肝纤维化的诊断准确率较高，可作为临床评估此类患者的重要检查方式。

Assessment on the Ultrasound Quantitative Detection for Liver Fibrosis in Patients with Hepatitis B

Objective To analyze the assessment value of ultrasonic quantitative detection for liver fibrosis in patients with hepatitis B. Methods One hundred and sixty patients with hepatitis B were selected. All patients underwent ultrasound quantitative detection and liver tissue biopsy. The thickness of liver capsules, spleen diameter and thickness, internal diameters of spleen portal vein and portal vein trunk as well as the thickness of gallbladder wall were studied in patients at different pathological stages, and the diagnostic accuracy of ultrasound quantitative detection for liver fibrosis in patients with hepatitis B was evaluated. Results The levels of each detection index in patients with hepatic fibrosis at S0-S2 stages were on the rise, but there were no significant differences among groups, and those in patients at S3, and S4 stages were significantly higher than those at stages S0 and S1 , with significant difference. The accuracy of ultrasonic quantitative detection for mild and moderate liver fibrosis as well as early liver cirrhosis was 92%, 97% and 82%, respectively. Conclusion With advantages of non-invasiveness and repeatability, the diagnostic accuracy of ultrasonic quantitative detection for liver fibrosis in patients with hepatitis B is satisfactory, which can be considered as an important examination method to assess liver fibrosis in patients with hepatitis B.