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尼莫地平对短暂性脑缺血发作后认知功能障碍的影响
引用本文:徐艳,章军建,杨四清. 尼莫地平对短暂性脑缺血发作后认知功能障碍的影响[J]. 临床内科杂志, 2007, 24(5): 331-332
作者姓名:徐艳  章军建  杨四清
作者单位:430071,武汉大学中南医院神经科;430071,武汉大学中南医院神经科;430071,武汉大学中南医院神经科
摘    要:目的 探讨短暂性脑缺血发作后认知功能障碍的干预措施.方法 随机选择短暂性脑缺血发作(TIA)患者,分为治疗组和对照组,治疗组除常规治疗外,给予尼莫地平90 mg/d口服,观察尼莫地平对简易智力状态检查(MMSE)及记忆功能的影响.结果 在TIA后对认知功能进行评分,治疗前两组的认知功能无明显差异,治疗后尼莫地平治疗组的MMSE及字词记忆、数字记忆、图形记忆与治疗前及对照组相比有显著改善.结论 尼莫地平可能对TIA的认知功能障碍有改善作用.

关 键 词:短暂性脑缺血发作  尼莫地平  认知功能
文章编号:1001-9057(2007)05-0331-02
修稿时间:2006-05-21

The influence of nimodipine on cognitive impairment after TIA
XU Yan,ZHANG Junjian,YANG Siqing. The influence of nimodipine on cognitive impairment after TIA[J]. Journal of Clinical Internal Medicine, 2007, 24(5): 331-332
Authors:XU Yan  ZHANG Junjian  YANG Siqing
Affiliation:Department of Neurology,Zhongnan hospital, Wuhan university, Wuhan 430071, China
Abstract:Objective To explore the treatment of cognitive impairment after TIA.Methods TIA patients were divided randomly into two groups.The patients of treatment group were given nimodipine 90mg/d.Mini-mental-status examination(MMSE)and memory function were investigated before and after TIA.Results MMSE and memory function of treatment group had improved better than plactogroup.Conclusion Nimodipine could improve the cognitive impairment after TIA.
Keywords:Transient ischemic attrack   Nimoclipine   Cognitive function
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