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Assessment of pro-vasopressin and pro-adrenomedullin as predictors of 28-day mortality in septic shock patients |
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| Authors: | Caroline Guignant Nicolas Voirin Fabienne Venet Françoise Poitevin Christophe Malcus Julien Bohé Alain Lepape Guillaume Monneret |
| Institution: | 1.Flow Cytometry Unit, Immunology Laboratory, H?pital E. Herriot, Hospices Civils de Lyon,Lyon cedex 03,France;2.INSERM U271, Hospices Civils de Lyon, H?pital E. Herriot, Service d’Hygiène, Epidémiologie et Prévention,Université de Lyon,Lyon,France;3.Intensive Care Units, Hospices Civils de Lyon, CH Lyon-Sud,Lyon,France |
| Abstract: | PurposeImprovements in survival after septic shock will most likely rely on our capacity to manage individualized therapies based on the measurement of rapidly accessible biomarkers. As the early phase of septic shock is dominated by severe alterations of the cardiovascular system, the predictive value for mortality of pro-vasopressin (pro-AVP) and pro-adrenomedullin (pro-ADM), two vasoactive pro-hormones, was assessed. |
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