| 膳食纤维与结直肠肿瘤的研究进展 |
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| 引用本文： | 袁凯涛.膳食纤维与结直肠肿瘤的研究进展[J].肠外与肠内营养,2011,18(3):182-184. |
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| 作者姓名： | 袁凯涛 |
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| 作者单位： | 中山大学附属第一医院胃肠外科; |
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| 摘 要： | 长久以来,膳食纤维被认为可以降低结直肠肿瘤发生风险.膳食纤维做为益生元,被肠内益生菌酵解,可产生多种短链脂肪酸,降低肠内致癌物浓度,加速致癌物的排出,影响胆汁酸代谢.但有少数前瞻性研究结果并不支持该假说,其抗结直肠肿瘤作用的机制尚需要进一步研究.
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| 关 键 词： | 膳食纤维 结直肠肿瘤 丁酸 益生元 |
Progress in dietary fiber and colorectal tumor research |
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| YUAN Kai-tao.Progress in dietary fiber and colorectal tumor research[J].Parenteral & Enteral Nutrition,2011,18(3):182-184. |
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| Authors: | YUAN Kai-tao |
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| Institution: | YUAN Kai-tao reviewing,SHI Han-ping checking (Department of General Surgery,First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,Guangdong,China) |
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| Abstract: | Dietary fibre has long been thought to be associated with a reduced risk of colorectal cancer.Dietary fiber,as prebotics which can be used by probiotics,increase various short-chain fatty acid(SCFA)production,lower carcinogens concentration,accelerate carcinogens eduction and affect the bile acid metabolism.Rencently,some perspective studies do not support this hypthesis.The mechanism of anti-colorectal cancer of dietary fiber need more further investigation. |
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| Keywords: | Dietary fiber Colorectal cancer Butyrate Prebiotics |
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