布洛芬口服滴剂药效学实验研究

目的：对布洛芬了滴剂与布洛芬片剂进行药效学比较。方法：采用布洛芬口服滴剂观察对角叉胶所致大鼠足跖炎性肿的抗炎作用、解热和镇痛作用；内毒素所致家兔体温升高的解热作用和醋酸所致小鼠疼痛的镇痛作用。结果：布洛芬口服滴剂有明显的抗炎、解热和镇痛作用。结论：布洛芬口服滴剂药效与片剂相同。

Experimental research on drug evaluation of ibuprofen oral drop]

OBJECTIVE: To make a pharmaceutical comparison between ibuprofen oral drop and ibuprofen tablet. METHODS: Using ibuprofen oral drop, we observed the anti-inflammatory and analgesic effects of ibuprofen oral drop on the inflammatory swelling of the rats' toe caused by diagonal carrageenin; its anti-thermic effect on the temperature rising of domestic rabbits caused by endotoxin; and its analgesic effect on mice's pain caused by acetic acid. RESULTS: Ibuprofen had obvious anti-inflammatory and analgesic functions. CONCLUSION: Ibuprofen oral drop has the same pesticide effect as that of ibuprofen tablet.