1037株病原菌分布及其主要病原菌耐药情况分析

目的分析佛山市南海区第三人民医院检出的病原菌分布及其主要病原菌耐药情况,为临床合理用药和控制医院感染提供依据。方法采用法国生物梅里埃公司ATB微生物鉴定仪对2010年1月至2011年12月从该院患者的各类标本中分离的1 037株病原菌进行鉴定,药敏试验采用琼脂纸片扩散法及法国生物梅里埃ATB药敏板条。结果检出病原菌以革兰阴性杆菌为主占58.4%、革兰阳性球菌次之占27.3%,真菌占13.2%,除真菌外的其他主要病原菌的抗菌药物耐药率普遍较高。结论医院容易发生医院感染,应加强其病原菌分布及其抗菌药物耐药情况监测,以指导临床合理用药,降低医院感染率。

Distribution of 1037 strains of pathogenic bacteria and antibiotic resistance of the main pathogenic bacteria analysis

Objective To analyze the distribution of pathogenic bacteria isolated from our hospital and the antibiotic resistance of the main pathogenic bacteria,to provide a basis for clinical rational drug use and control the hospital infection.Methods 1 037 strains of pathogenic bacteria separated from patients in our hospital during Jan 2010-Dec 2011 were identified by ATB biomerieux from France and detected the antibiotic resistance by Kirby-Bauer（K-B） agar tape diffusion and drug sensitivity test tape of ATB biomerieux from France.Results The Gram-negative bacteria（58.4%） were the main pathogenic bacteria,as followed by Gram-positive bacteria（27.3%）,and fungi（13.2%）.The antibiotic resistance rates of the main pathogenic bacteria except fungi were high.Conclusion Patients easily suffered hospital infection,it should strengthen the monitoring of the distribution of pathogenic bacteria and their antibiotic resistance so as to help the doctors to choose the antibiotics reasonably and reduce the rate of hospital infection.