柳州市某三甲医院2009～2011年人类免疫缺陷病毒初筛结果分析

目的了解柳州某三甲医院2009～2011年84 303例门诊和住院患者人类免疫缺陷病毒(HIV)感染情况。方法采用酶联免疫吸附试验检测HIV抗体,结果阳性者用原有试剂和另外一种不同厂家的试剂进行复检,复检结果均阳性或一阴一阳的作为初筛阳性样本并送当地疾病预防控制中心进行确认试验。通过数据统计分析,了解近3年HIV抗体阳性率、感染途径等情况。结果 84 303例患者,HIV抗体阳性患者843例(1.00%),合并梅毒抗体阳性标本有150例(17.79%),各年间HIV阳性检出率差异有统计学意义(P<0.05)。结论柳州地区HIV感染一直处于高发状态,应加强对入院患者HIV抗体检测,尽早发现感染者,防止疾病进一步传播,同时降低职业暴露的风险。

Analysis on the results of HIV antibody screening test in a center hospital in Liuzhou from 2009 to 2011

Objective To analyze the status of 84 303 outpatients and inpatients with HIV infection in a center hospital in Liuzhou from 2009 to 2011. Methods HIV antibody was detected by ELISA,and the samples of HIV an- tibody positive was rechecked using the same reagent and another one of different manufacture. The samples with re- view test results at least once positive were as the screening positive samples,and were sent to local CDC for confir- mation test. The data was analyzed hy statistical analysis to understand the HIV-positive rate and the route of infec- tion in the past three years. Results This study include 84 303 patients,843 cases （1.00%） were positive. 150 cases （17.79%） were HIV-positive mergered TP antibody positive. The difference of the positive rate of every year was significant. Conclusion Liuzhou area has been a high accidence of HIV infection. HIV antibody test of the hospital patients should be strengthened to detect the infection early, and to combat the spread of the disease, while reducing the risk of occupational exposure.