| Expression of IL-1β and TNF-α in MCMV Myocarditis and Its Role |
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| 作者姓名： | 唐省三 廖玉华 陈志坚 高翔 董继华 |
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| 作者单位： | Institute of Cardiology，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Institute of Cardiology，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Institute of Cardiology，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Institute of Cardiology，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Viral Reseach Laboratory，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology Wuhan 430022，China，Wuhan 430022，China，Wuhan 430022，China，Wuhan 430022，China，Wuhan 430022，China |
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| 基金项目： | This project was supported by a grant from National Natu-ral Sciences Foundation of China (No .39970306) . |
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| 摘 要： | Autoi mmune myocarditis in Coxsackievirus B3(CB3)-infected mice is associated with infiltrationof the heart by inflammatory cells that secreteTNF-αand IL-1[1].In this study we examine theexpression of cytokines , TNF-αand IL-1βpro-duced locallyinthe heart inresponse to MCMVin-fectionin order to determine their potential role inthe development of acute myocarditis .1MATERIALS AND METHODS1 .1Reagents and AntibodiesMonoclonal goat anti-mouse IL-1β, TNF-αanti-body and SABC …
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| 关 键 词： | MCMV Myocarditis IL-1β TNF-α Immunohistochemistry |
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