焦虑对老年DMCI患者认知功能和颈动脉内膜-中层厚度的影响

目的：：探讨焦虑对老年2型糖尿病合并脑梗死(DMCI）患者认知功能和颈动脉内膜-中层厚度(IMT）的影响。方法：100例老年DMCI患者根据是否存在焦虑分为观察组62例（合并焦虑）和对照组38例（不合并焦虑）。采用蒙特利尔认知评估量表(MoCA）评价两组患者的认知功能，颈动脉超声检查测量IMT。结果：观察组患者IMT显著高于对照组、MoCA评分显著低于对照组(P＜0.01）。观察组患者焦虑评分与MoCA评分呈负相关、与IMT呈正相关(P＜0.01），MoCA评分与IMT呈负相关(P＜0.01）。结论：合并焦虑可加重DMCI患者的认知功能障碍及颈动脉粥样硬化程度，导致患者生活质量下降。

EFFECTS OF ANXIETY ON COGNITIVE FUNCTION AND INTEIMA-MEDIA THICKNESS OF ELDERLY DMCI PATIENTS

ABSTRACT]Objective:To investigate the effects of anxiety on cognitive function and intima-media thickness (IMT) of elderly patients with type 2 diabetes complicated with cerebral infarction (DMCI). Methods:100 elderly DMCI patients were divided into observation group (n=62, with anxiety) and control group (n=38, no anxiety). MoCA scale was used to evaluate the cognitive function of patients, and color ultrasound to measure IMT of common carotid artery. Results:IMT of patients in observation group was obviously higher than patients in control group, but MoCA score was obviously lower (P<0.01). The anxiety score of patients in observation group was negatively correlated with MoCA score, but positively correlated with IMT (P<0.01);And MoCA score was negatively correlated with IMT (P<0.01). Conclusions:Anxiety may aggravate cognitive dysfunction and degree of carotid atherosclerosis, and cause declining of the living quality.