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迷走神经劈开术治疗大鼠声带麻痹的实验研究
引用本文:刘宏建,娄卫华.迷走神经劈开术治疗大鼠声带麻痹的实验研究[J].临床耳鼻咽喉头颈外科杂志,2010,24(6).
作者姓名:刘宏建  娄卫华
作者单位:1. 河南省人民医院耳鼻咽喉科,郑州,450003
2. 郑州大学一附院耳鼻咽喉科
摘    要:目的:探讨劈开颈段迷走神经中喉返神经支修复大鼠声带麻痹的手术方法和手术效果。方法:首先运用剥离法及乙酰胆碱酯酶组织化学染色方法确定喉返神经支在颈部迷走神经中的位置,将60只SD大鼠被分为3组,实验组为迷走神经劈开术吻合组,切断右侧喉返神经,将其远断段与劈开的颈段迷走神经的喉返支吻合。对照组为喉返神经端端吻合组,切断右侧喉返神经后立即行神经吻合。正常组不做处理。术后3个月利用纤维喉镜及神经肌电图观察声带活动及神经再生情况。结果:喉返神经束位于颈段迷走神经前内侧,单独成束,直径为总干的1/4。术后3个月2种手术方法效果差异无统计学意义(P>0.05)。结论:对喉返神经在迷走神经中准确定位,为手术操作提供了重要的解剖标志。迷走神经劈开术为喉返神经修复术提供一种新的手术方法。

关 键 词:喉返神经  迷走神经  声带麻痹  

Functioning remobilization of the paralyzed vocal cord using the split-vagus nerve procedure in rats
LIU Hongjian,LOU Weihua.Functioning remobilization of the paralyzed vocal cord using the split-vagus nerve procedure in rats[J].Journal of Clinical Otorhinolaryngology,2010,24(6).
Authors:LIU Hongjian  LOU Weihua
Institution:1Department of Otolaryngology/a>;Henan Province People's Hospital/a>;Zhengzhou/a>;450003/a>;China/a>;2Department of Otolaryngology/a>;the First Affiliated Hospital/a>;Zhengzhou University
Abstract:Objective:To locate the recurrent laryngeal nerve fascicles in vagus and investigate the effect of the splilt-vagus nerve procedure to repair the paralyzed vocal cord in rats.Method:The method of dissection and acetylcholinesterase histochemical staining of neural fibers were used to locate the recurrent laryngeal nerve fascicles in vagus.Then 60 SD rats were divided into three groups.In experimental group right recurrent laryngeal nerve were incised and anastomosed to recurrent laryngeal nerve fascicles in...
Keywords:recurrent laryngeal nerve  vagus nerve  paralyed vocal cord  
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