急性脑梗死患者血清钙、镁含量的变化及其临床意义

目的:探讨急性脑梗死(ACI)患者血清钙、镁(Ca2+、Mg2+)含量的变化与病情及预后的关系。方法:检测37例ACI患者发病早期及治疗2周后血清Ca2+、Mg2+含量,并与31例健康中老年人进行对照。结果:梗死组血清钙、镁含量均低于健康对照组(P<0.01),梗死组中轻、中、重3型比较,其血清Ca2+、Mg2+含量梯度为重型<中型<轻型(P<0.05,P<0.01),治疗2周后,血清Ca2+、Mg2+含量有较大程度回升(P<0.01)。结论:ACI早期血清Ca2+、Mg2+含量均明显降低,病情越重,降低越明显,随病情好转,血清Ca2+、Mg2+含量回升,因此,血清Ca2+、Mg2+含量可作为判断病情及评估预后的指标之一。

Changes of Serum Calcium and Magnesium Levels in Acute Cerebral Infarction and Its Clinical Significance

Objective:To explore the relationship between serum calcium and magnesium concentration and acute cerebral infarction and elucidate its clinical significance. Method: The serum calcium and magnesium concentration was determined in 31 healthy people (control group) and 37 acute cerebral infarction patients before and after two weeks of study.According to the clinical nerve deficiency scale, the cerebral infarction patients was divided into three subgroups: Mild cerebral infarction, moderate cerebral infarction and severe cerebral infarction. Result:Compared with control group serum calcium and magnesium concentrations in all three subgroups of acute cerebral infarction patients were significantly lower (P<0.01),and serum calcium and magnesium concentration were negatively correlate with severity of the disease. Serum calcium and magnesium concentration increased after two weeks treatment(P<0.01) though they were still lower than those in control group(P<0.01). Conclusion:The Serum calcium and magnesium concentration decrease in acute cerebral infarction patients. The degree of decrease was correlated with the clinical nerve deficiency scales, the concentration increased with patients recovery.A prognosisindex of the patients was evaluated by calcium and magnesium concentration changes in serum.