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| 骨髓间充质干细胞联合纤维蛋白胶修复大鼠牙槽骨缺损的研究 | |
| 引用本文： | Zhang L,Ding Y,Shao JL,Dong JS. 骨髓间充质干细胞联合纤维蛋白胶修复大鼠牙槽骨缺损的研究[J]. 华西口腔医学杂志, 2011, 29(2): 125-128. DOI: 10.3969/j.issn.1000-1182.2011.02.004 |
| 作者姓名： | Zhang L Ding Y Shao JL Dong JS |
| 作者单位： | 第四军医大学口腔医院正畸科, 西安710032 |
| 基金项目： | 国家自然科学基金资助项目 |
| 摘 要： | 目的 评价骨髓间充质干细胞(BMSCs)和纤维蛋白胶(FG)作为种子细胞和支架材料修复大鼠牙槽骨缺损的效果.方法 30只SD大鼠随机分成A、B组,建立SD大鼠上颌牙槽骨缺损模型,联合植入BMSCs和FG复合物,A组对照侧单纯植入FG,B组对照侧为空白对照.利用上颌骨实验区切片苏木精-伊红染色及Micro-CT扫描观察成... |
| 关 键 词： | 骨髓间充质干细胞 纤维蛋白胶 组织工程 牙槽骨缺损 |
| 收稿时间： | 2011-04-25 |
| 修稿时间： | 2011-04-25 |
Study of alveolar bone defects reparation by combination of bone marrow stromal cells and fibrin glue |
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| Zhang Liang,Ding Yin,Shao Jin-Ling,Dong Jin-Shan. Study of alveolar bone defects reparation by combination of bone marrow stromal cells and fibrin glue[J]. West China journal of stomatology, 2011, 29(2): 125-128. DOI: 10.3969/j.issn.1000-1182.2011.02.004 | |
| Authors: | Zhang Liang Ding Yin Shao Jin-Ling Dong Jin-Shan |
| Affiliation: | Dept. of Orthodontics, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, |
| Abstract: | Objective To explore the effects and feasibility of the repairing alveolar bone by combination of bone marrow stromal cells(BMSCs) and fibrin glue(FG).Methods BMSCs were obtained from the sucking mouse and then separated,cultured to the second generation to get ready for use.The available cells were combined with FG and then immediately implanted into the defect that had been established in one lateral maxilla of 30 SD rats.At the same time pure FG without BMSCs was implanted into the other side.The rats we... |
| Keywords: | bone marrow stromal cells fibrin glue tissue engineering alveolar bone defect |
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