| 胶原-羟磷灰石复合膜引导骨组织再生的动物实验研究 |
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| 引用本文： | Jin Q,Wang XM,Wang XF,Li XD,Ma JF. 胶原-羟磷灰石复合膜引导骨组织再生的动物实验研究[J]. 华西口腔医学杂志, 2011, 29(1): 21-26. DOI: 10.3969/j.issn.1000-1182.2011.01.006 |
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| 作者姓名： | Jin Q Wang XM Wang XF Li XD Ma JF |
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| 作者单位： | 1.温州医学院附属口腔医院口腔修复科, 温州325027;2.四川大学生物材料工程技术研究中心, 成都610064 |
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| 摘 要： | 目的 探讨自制胶原-羟磷灰石(COL-HA)复合膜修复SD大鼠颅骨缺损的效果.方法在24只SD大鼠的颅顶骨上各制备4个缺损,其中左、右侧缺损区分别覆盖COL-HA复合单层致密膜(第2组)和COL-HA复合双层膜(第3组),额骨缺损区保留作为空白对照(第1组),枕骨缺损区覆盖Bio-Gide膜作为对比(第4组).术后2、...
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| 关 键 词： | 引导骨组织再生 胶原 羟磷灰石 骨缺损 |
| 收稿时间： | 2011-02-25 |
| 修稿时间： | 2011-02-25 |
The efficacy of collagen-hydroxyapatite composite membrane on bone regeneration |
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| Jin Qiong,Wang Xiao-min,Wang Xiao-fei,Li Xu-dong,Ma Jian-feng. The efficacy of collagen-hydroxyapatite composite membrane on bone regeneration[J]. West China journal of stomatology, 2011, 29(1): 21-26. DOI: 10.3969/j.issn.1000-1182.2011.01.006 |
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| Authors: | Jin Qiong Wang Xiao-min Wang Xiao-fei Li Xu-dong Ma Jian-feng |
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| Affiliation: | 1. Dept. of Prosthodontics, Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027 China; 2. Biomaterial and Engineering Research Center in Biomaterial, Sichuan University, Chengdu 610064, China |
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| Abstract: | Objective To investigate the efficacy of a new collagen-hydroxyapatite(COL-HA) composite membrane on bone regeneration of SD rat cranial defects.Methods Four defects were produced in the calvaria of 24 SD rats.The animals were divided into four groups:Empty defects without membrane(group 1);defects covered by COL-HA single-layer dense membranes(group 2);defects covered by COL-HA double-layer membranes(group 3); defects covered by Bio-Gide membranes(group 4).At 2,4,8 and 12 weeks after surgery,6 rats were sa... |
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| Keywords: | guide bone regeneration collagen hydroxyapatite bone defect |
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