Construction of retroviral vectors to induce a strong expression of human interferon-β gene in human hepatoma cells 期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Construction of retroviral vectors to induce a strong expression of human interferon-β gene in human hepatoma cells

作者姓名：	曹广文高军杨文国戚中田杜平孔宪涛

作者单位：	Department of Microbiology，Second Military Medical University，Shanghai，200433

摘要：	ClassIinterferonisapotent1mmunemodu-latingfactorinvivo,andplaysanimportantrolelnactivatinganti-tumorcytotoxicTlymphocytesandnonuspecificeffectorcellssuchasNKcellsLlJ.ln-terferonandmanyothercytokinegeneswereintro-ducedintotumorcells,tumorinterstitialcellsandtumorinfiltratinglymphocytes['-']inordertosustainaneffectiveanti-tumorconcentrationofcy-tokinelocatedattumorsites.Itwasshownthatsomecytokinegenemodifiedtumorcellslosttheirtumorigenicityandinhibitedthegrowthofparentaltumorinanimalmodels.Pra…
本文献已被 CNKI 等数据库收录！