Effects of glutamate and aspartate on growth performance,serum amino acids,and amino acid transporters in piglets |
| |
Authors: | Yuying Li Hui Han Jie Yin Jie Zheng Xiaotong Zhu |
| |
Affiliation: | 1. Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, People's Republic of China;2. National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Changsha, Hunan, People's Republic of China;3. Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Changsha, Hunan, People's Republic of China;4. Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan, People's Republic of China;5. University of Chinese Academy of Sciences, Beijing, People's Republic of China;6. Department of Animal Science, Hunan Agriculture University, Changsha, Hunan, People's Republic of China;7. College of Life Science, Guangxi Normal University, Guilin, Guangxi, People's Republic of China |
| |
Abstract: | This study mainly investigated the effects of different dietary levels of glutamate (Glu) and aspartate (Asp) on growth performance, blood amino acids, and amino acid transporters in piglets. Forty-two healthy piglets were randomly divided into six groups (n?=?7): a control group in which piglets were fed 2.9% Glu and 1.5% Asp and other groups in which piglets received 1.3% or 1.7% Asp and 2.6%, 3.2%, or 3.5% Glu for 21 days. Growth performance, serum amino acid profiles from the mesenteric vein, portal vein, and anterior vena cava, and amino acid transporters in the liver were determined. The results showed that lower doses of Asp promoted growth and enhanced the amino acids, while high doses of Asp and Glu reduced growth and the amino acid pool in piglets (P?0.05). Meanwhile, 3.2% Glu increased branched chain amino acids in the portal vein and anterior vena cava (P?0.05). 3.5% Glu downregulated SLC7A1, SLC7A7, and SLC6A19 expression in the liver (P?0.05). Collectively, these results indicated that different dietary doses of Glu and Asp influenced growth performance and serum amino acid. |
| |
Keywords: | Piglets glutamate aspartate amino acid amino acid transporters |
|
|