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螺内酯致男性乳腺增生1例
引用本文:周旭,陈红鸽,吴荣荣,刘淼.螺内酯致男性乳腺增生1例[J].中国药物应用与监测,2010,7(3):161-161,174.
作者姓名:周旭  陈红鸽  吴荣荣  刘淼
作者单位:解放军302医院药学部临床药学室,北京,100039
摘    要:1例36a男性患者,因肝硬化腹水选用呋塞米和螺内酯进行利尿治疗,服药后第2天,患者自觉乳腺发热并有明显胀感。经进一步了解,该患者此前曾2次服用螺内酯,发生明显乳腺增生,当时乳腺局部有硬结,触压疼痛,停用螺内酯后逐渐恢复正常。鉴于此,即停用螺内酯,1周后患者乳腺发热感和胀感等不良反应症状逐渐消失。

关 键 词:螺内酯  不良反应  男性  乳腺增生

One case report of male galactophore hyperplasia induced by spironolactone
Authors:ZHOU Xu  CHEN Hong-ge  WU Rong-rong  LIU Miao
Institution:(Department of Clinical Pharmacy,302 Hospital of PLA,Beijing 100039,China)
Abstract:A 36-year-old man received furosemide and spironolactone for curing ascites due to cirrhosis.The man felt galactophore fevering and distending after administration for two days.Subsequently,the patient presented that obvious hyperplasia of mammary glands with local scleroma and tenderness had ever appeared when spironolactone was twice administered,and symptoms recovered to normal gradually after drug withdrawal.In view of this,spironolactone was discontinued immediately,then galactophore fevering and distending disappeared a week later.
Keywords:Spironolactone  Adverse reaction  Male  Galactophore hyperplasia
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