| Rho激酶与动脉血管再狭窄的研究进展 |
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| 引用本文： | 苗志林,关启刚,曾定尹.Rho激酶与动脉血管再狭窄的研究进展[J].心血管病学进展,2006,27(Z1):66-69. |
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| 作者姓名： | 苗志林 关启刚 曾定尹 |
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| 作者单位： | 1. 沈阳医学院沈洲医院,沈阳市心血管病医院,辽宁,沈阳,110002
2. 中国医科大学第一临床学院循环内科,辽宁,沈阳,110001 |
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| 摘 要： | Rho激酶是具有信息传导和分子开关功能的信号多肽,与动脉粥样硬化、高血压、冠脉痉挛、心肌缺血等主要心血管病的发生和发展关系密切,并通过多种途径参与血管损伤后内膜增殖和再狭窄的调控过程。现简要综述再狭窄发病过程中Rho激酶的作用机制及Rho激酶抑制剂预防再狭窄的实验结果。
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| 关 键 词： | Rho激酶 再狭窄 |
| 文章编号： | 1004-3934(2006)增刊-0066-04 |
| 修稿时间： | 2005年12月12 |
Progress on Rho-kinase and Vascular Artery Restenosis |
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| MIAO Zhi-lin,GUAN Qi-gang,ZENG Ding-yin.Progress on Rho-kinase and Vascular Artery Restenosis[J].Advances in Cardiovascular Diseases,2006,27(Z1):66-69. |
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| Authors: | MIAO Zhi-lin GUAN Qi-gang ZENG Ding-yin |
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| Abstract: | Rho-kinase is a kind of polypeptide served as a molecular switch with the function of signal transduction.It also closely related with the genesis and development of main cardiovascular diseases(such as atherosclerosis,hypertension,coronary artery spasm and myocardial ischemia).Rho-kinase take part in the genesis of restenosis through many different ways.The role of Rho-kinase played in the genesis of restenosis and the experimental results about Rho-kinase inhibitors were reviewed in this article. |
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| Keywords: | Rho-kinase restenosis |
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