Evaluation of functional,autonomic and inflammatory outcomes in children with asthma |
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Authors: | Evelim Leal de Freitas Dantas Gomes Dirceu Costa |
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Institution: | Evelim Leal de Freitas Dantas Gomes, Rehabilitation Sciences, Physical Therapy Course, University Nove de Julho, São Paulo 01504-001, BrazilDirceu Costa, Postgraduate Program in Rehabilitation Sciences, University Nove de Julho, São Paulo 01504-001, Brazil |
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Abstract: | Asthma is common in childhood. This respiratory disease is characterized by persistent inflammation of the airways even when the child is not in thethroes of an attack. Chronic inflammation is caused by an imbalance between pro-inflammatory and antiinflammatory mechanisms as well as autonomic dysfunction, which plays an important role in the pathogenesis and control of this condition. The impact of these physiopathological aspects leads to inactivity and a sedentary lifestyle, which exerts an influence on functional capacity and control of the disease. The main objective of non-pharmacological therapy is the clinical control of asthma and the minimization of airway obstruction and hyperinflation during an attack. These factors can be controlled with noninvasive ventilation. The aim or the present review was to describe important neural, inflammatory and functional mechanisms that affect children with asthma. |
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Keywords: | Asthma Child Continuous positive airway pressure Noninvasive ventilation Autonomic nervous system Functional capacity Inflammatory mechanisms Evaluation |
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