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West Nile Virus RNA in Tissues from Donor Associated with Transmission to Organ Transplant Recipients |
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| Authors: | Dianna M. Blau Ingrid B. Rabe Julu Bhatnagar Rachel Civen Kavita K. Trivedi Dominique Rollin Susan N. Hocevar Matthew Kuehnert J. Erin Staples Sherif R. Zaki Marc Fischer the West Nile Virus Transplant-Associated Transmission Investigation Team |
| Affiliation: | Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D.M. Blau, J. Bhatnagar, D. Rollin, S.N. Hocevar, M. Kuehnert, S.R. Zaki); ;Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (I.B. Rabe, J.E. Staples, M. Fischer); ;Los Angeles County Department of Public Health, Los Angeles, California, USA (R. Civen); ;California Department of Public Health, Richmond, California, USA (K. Trivedi) |
| Abstract: | We identified West Nile virus (WNV) RNA in skin, fat, muscle, tendon, and bone marrow from a deceased donor associated with WNV transmission through solid organ transplantation. WNV could not be cultured from the RNA-positive tissues. Further studies are needed to determine if WNV can be transmitted from postmortem tissues. |
| Keywords: | West Nile virus WNV RNA organ transplantation tissues viruses solid organ transplantation organs transplant immunodeficiency organ donor virus transmission |