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Premixed 50% nitrous oxide and oxygen: theoretical recalls and practical modalities
Authors:Boulland P  Favier J-C  Villevieille T  Allanic L  Plancade D  Nadaud J  Ruttimann M
Institution:1. Site de référence pédiatrique labellisé « drépanocytose », hôpital Robert-Debré, Assistance publique–Hôpitaux de Paris, 48, boulevard Sérurier, 75020 Paris, France;2. Centre d’évaluation et de traitement de la douleur, hôpital Robert-Debré, Assistance publique–Hôpitaux de Paris, 48, boulevard Sérurier, 75020 Paris, France;3. Service de pédiatrie générale, hôpital Robert-Debré, Assistance publique–Hôpitaux de Paris, 48, boulevard Sérurier, 75020 Paris, France;4. URC CIC Descartes, hôpital Necker/Cochin, 149, rue de Sèvres, 75015 Paris, France;1. Unité de médecine polyvalente à orientation gériatrique, centre hospitalier Louis-Raffalli, chemin Auguste-Girard, 04100 Manosque, France;2. Unité ESPRI-Biobase, plateforme d’aide à la recherche clinique, hôpitaux de Brabois, CHRU de Nancy, bâtiment Recherche, rue du Morvan, 54500 Vandœuvre-les-Nancy, France
Abstract:The concept of premixed 50% nitrous oxide and oxygen dated back to 1961 in England, where it is commercialised under the name Entonox. In France, after a so marginal use, premixed 50% nitrous oxide and oxygen now knows such a revival since we first consider the pain provoked by the cure. To use correctly premixed 50% nitrous oxide and oxygen, we need to know the main properties of the nitrous oxide. The four commercial versions, now on the market, are presented (Kalinox, Medimix, Antasol, Oxynox. Except a few contraindications, these indications are large, as well at hospital as outside. In less than 10% of the cases, side effects are possible. Conditions of administration are given in details. The limits of the technic and the particular precautions of use are precised.
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