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太仓农村地区女性胆囊结石危险因素病例对照研究
引用本文:庄勋,李立明. 太仓农村地区女性胆囊结石危险因素病例对照研究[J]. 中华流行病学杂志, 2000, 21(1): 44-47
作者姓名:庄勋  李立明
作者单位:北京医科大学公共卫生学院流行病学教研室,100083
摘    要:目的 概括太仓农村地区女性胆结石的危险因素。方法 选择5个村,对35 ̄79岁的居民进行B超检查,共检出女性胆囊结石例144例(其中现患病105例,既往手术病人39例)、先取女性随机人群对照371例,实施以人群为基础的病例对照研究。结果 年龄(OR=1.80)、胆石症家族史,高血压史、饮用深井水、喜食肥肉、多孕次、绝经等因素与胆囊结石的OR值有显著性。结论 年龄、胆石症阳性家族史、高血压、喜食肥肉、

关 键 词:胆囊结石 危险因素 病例对照 女性
收稿时间:1999-03-22
修稿时间:1999-03-22

A case-control study of gallstone disease in female population in Taicang
ZHUANG Xun and LI Liming. A case-control study of gallstone disease in female population in Taicang[J]. Chinese Journal of Epidemiology, 2000, 21(1): 44-47
Authors:ZHUANG Xun and LI Liming
Affiliation:ZHUANG Xun(Department of Epidemiology, Beijing Medical University, Beijing 100083, China)LI Liming(Department of Epidemiology, Beijing Medical University, Beijing 100083, China)
Abstract:Objective To investigate the risk factors of gallstone disease in female population in Taicang. Methods A case-control study conducted on 144 cases and 371 controls aged 35-79 years in five villages. Diagnosis of gallstone disease was assessed by real-time ultrasonography. The case was considered as presence of gallstones at echograph and previous cholecytectomy. The controls were selected from a random sample of female participates. Results Through univariate and multivariate analysis,gallstone disease was significantly associated with age ( OR =1.80), family history of gallstone disease ( OR = 3.66), hypertension ( OR =1.93),fat intake ( OR =1.77), number of pregnancies ( OR =1.44) and menopause ( OR =1.67). Drinking water from deep well ( OR =0.54) was inversely associated with gallstone disease. Conclusion The main risk factors of female gallstone disease were age, family history of gallstone disease, fat intake,number of pregnancy and menopause. Drinking water from deep well was a protective factor of gallstone disease.
Keywords:Cholelithiasis  Risk factor  Case-control study  
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