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Lipoxygenase inhibitory constituents fromIndigofera oblongifolia |
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| Authors: | Ahsan Sharif Ejaz Ahmed Abdul Malik Naheed Riaz Nighat Afza Sarfraz Ahmad Nawaz Muhammad Arshad Muhammad Raza Shah Muhammad Iqbal Choudhary |
| Affiliation: | International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan. |
| Abstract: | Indigin, alkylated xanthene (1) and indigoferic acid (2) have been isolated from the chloroform soluble fraction of Indigofera oblongifolia, along with beta-sitosterol (3) and 3-hydroxybenzoic acid (4), which are reported for the first time from this species. Their structures were determined through spectroscopic techniques. Both the new compounds 1 and 2 showed significant activity against enzyme lipoxygenase, while 2 further showed moderate inhibition against BChE. |
| Keywords: | Indigofera oblongifolia Fabaceae Lipoxygenase inhibition |
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