晚期妊娠引产临床观察

目的 比较米索前列醇（简称米索）、催产素、小剂量米索＋催广素用于晚期妊娠引产的效果。方法 100例孕37～42周的单胎头位产妇，均具有引产指征，随机分为A组（28例）、B组（35例）及C组（37例），分别给予阴道后穹舒降置入米索、静滴催产素以及小剂量米索加催加素引产，比较三组宫颈评分、总产程、分娩方式、出血量、新生儿Apgar计分、药物副反应差异。结果 C组分别与A、B组比较，平均引产成功率高，而平均总产程短、胎儿窘迫率、剖宫产率低（P〈0．05），出血量、新生儿Apgar评分比较无显著差异（P〉0．05）。结论 小剂量米索＋催产素用于晚期妊娠引产安全有效。

Clinical Study of Induced Labor in Late Pregnancy

Objective To compare the effect of misoprostol, oxytocin, combined application of low dose misoprostol and oxytocin in the induced labor in late pregnancy. Methods 100 cases of 37 to 42 weeks pregnancy with indication of induced labor were randomly divided into group A(n=28), group B(n=35), group C(n=37) and treated with misoprostol in vaginal fornix, oxytocin IV drop, and combination of low dose misoprostol and oxytocin respectively. Comparative analysis was performed in terms of entire labor duration, deliver methods, blood loss, Apgar scoring of neonate, and side-effect of drugs. Results Compared with group A and B, group C showed no significant difference in terms of blood loss and neonate Apgar scoring, whereas demonstrated significantly higher induced rate, shorter entire labor duration, lower fetal distress rate and cesarean section rate. Conclusion Application of low dose misoprostol associated with oxytocin is safe and effective in induced labor in late pregnancy.