| 657例抗感染药致不良反应分析 |
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| 引用本文： | 张海霞,葛卫红,吴宝萍.657例抗感染药致不良反应分析[J].中国药房,2008,19(29):2296-2298. |
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| 作者姓名： | 张海霞 葛卫红 吴宝萍 |
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| 作者单位： | 南京大学医学院附属鼓楼医院药剂科,南京市,210008 |
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| 摘 要： | 目的:了解我院抗感染药致不良反应发生的特点与一般规律。方法:对我院2006年药品不良反应(ADR)监测室收集到的657例抗感染药致ADR报告进行汇总分析。结果:引起ADR的抗感染药涉及13大类49个品种。657例ADR中,>60a发生率最高,占30.14%;喹诺酮类引起的ADR居首位,其次为头孢菌素类、青霉素类等;ADR的临床表现主要为皮肤及其附件损害(占53.12%),其次为消化系统、神经系统损害等。结论:抗感染药发生ADR与多种因素相关。临床在使用时应引起足够的重视,以减少ADR的发生。
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| 关 键 词： | 药品不良反应 抗感染药 合理用药 |
Adverse Drug Reactions Induced by Anti - infectives: Analysis of 657 Cases |
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| ZHANG Hai-xia,GE Wei-hong,WU Bao-ping.Adverse Drug Reactions Induced by Anti - infectives: Analysis of 657 Cases[J].China Pharmacy,2008,19(29):2296-2298. |
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| Authors: | ZHANG Hai-xia GE Wei-hong WU Bao-ping |
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| Institution: | (Dept. of Pharmacy, The Affiliated Drum Tower Hospital of Medical School of Nanjing University, Nanjing 210008, China) |
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| Abstract: | OBJECTIVE： To investigate the characteristics and regularities of adverse drug reactions （ADR） induced by anti infective drugs in our hospital. METHODS： 657 ADR cases induced by anti - infective drugs collected by the ADR monitoring center in our hospital in 2006 were classified and analyzed. RESULTS： 13 categories （49 kinds） of anti-infective drugs were involved in the total 657 ADR cases. Of which, those patients aged above 60 years accounted for 30.14%. The ADR were chiefly induced by quinolones, followed by cephatosporins and penicillins etc, which chiefly manifested as lesion of skin and its aeeessories （53.12%）, followed by the lesions of digestive system and nervous system etc. CONCLUSION： Multiple factors contributed to the ADR, to which great importance should be attached so as to reduce the incidence of ADR induced by anti - infeetives. |
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| Keywords: | Adverse drug reactions Anti- infectives Ralional administration |
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