| 红曲抗炎作用的实验研究 |
| |
| 引用本文： | 王炎焱,赵征,黄烽,任建平. 红曲抗炎作用的实验研究[J]. 中国新药杂志, 2006, 15(2): 96-98 |
| |
| 作者姓名： | 王炎焱 赵征 黄烽 任建平 |
| |
| 作者单位： | 1. 解放军总医院风湿科,北京,100853
2. 军事医学科学院放射医学研究所,北京,100850 |
| |
| 摘 要： | 目的：研究红曲的抗炎作用。方法：急性抗炎模型采用巴豆油致小鼠耳肿胀模型和角叉菜胶致大鼠足肿胀模型，慢性抗炎模型采用棉球植入小鼠腹腔致肉芽肿模型。以布洛芬作阳性对照，并设洛伐他汀高、低剂量组。比较红曲与洛伐他汀的抗炎作用。结果：红曲对巴豆油致小鼠耳肿胀、角叉菜胶致大鼠足肿胀和棉球致小鼠腹腔肉芽肿均有显著的抑制作用，与洛伐他汀的抗炎作用相近。结论：红曲具有显著的抗炎作用。
|
| 关 键 词： | 红曲 抗炎作用 洛伐他汀 |
| 文章编号： | 1003-3734（2006）02-0096-03 |
| 收稿时间： | 2005-05-31 |
| 修稿时间： | 2005-05-31 |
Anti-inflammatory effects of red yeast rice |
| |
| WANG Yan-yan,ZHAO Zheng,HUANG Feng,REN Jian-ping. Anti-inflammatory effects of red yeast rice[J]. Chinese Journal of New Drugs, 2006, 15(2): 96-98 |
| |
| Authors: | WANG Yan-yan ZHAO Zheng HUANG Feng REN Jian-ping |
| |
| Affiliation: | 1 Department of Rheumatology, Chinese PLA General Hospital, Belting 100853, China ;2 Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China |
| |
| Abstract: | Objective:To evaluate anti-inflammatory effects of red yeast rice. Methods:Acute inflammatory reaction models employing croton oil as inflammagen to induce mouse ear edema and carrageenan as inflammagen to induce rat paw swelling, and a chronic inflammatory reaction model placing cottons into abdominal cavity of rats to induce granuloma were set up to test anti-inflammatory activity of red yeast rice. Ibuprofen and lovastatin were used as the positive control. Results:Red yeast rice showed significant inhibitions of inflammatory activities in all models and a similar inhibition of inflammatory effects as lovastatin. Conclusion:Red yeast rice is effective against inflammation. |
| |
| Keywords: | red yeast rice anti-inflammatory effect lovastatin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
