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胸痛患者血栓前体蛋白及心肌肌钙蛋白I的检测意义
引用本文:于小红,魏美芳,吴翔,俞燕,李静.胸痛患者血栓前体蛋白及心肌肌钙蛋白I的检测意义[J].南通医学院学报,2005,25(6):412-413.
作者姓名:于小红  魏美芳  吴翔  俞燕  李静
作者单位:南通大学附属医院心内科,南通,226001
摘    要:目的:探讨血栓前体蛋白(TpP)和心肌肌钙蛋白Ⅰ(cTnI)在急诊胸痛患者中的检测意义。方法:急诊胸痛患者106例,其中急性心肌梗死患者36例、不稳定型心绞痛患者38例及非冠心病患者32例。利用酶联免疫分析法检测血浆中血栓前体蛋白(TpP)的含量和心肌肌钙蛋白Ⅰ(cTnI)。结果:急性心肌梗死(AMI)组TpP水平显著高于不稳定型心绞痛(UA)组及非冠心病组(P〈0.01);AMI组cTnI阳性率显著高于UA组(P〈0.01)及非冠心病组(P〈0.01)。结论:血浆TpP、及cTnI可作为急诊胸痛患者鉴别诊断的敏感指标。

关 键 词:急性心肌梗死  不稳定型心绞痛  血栓前体蛋白  心肌肌钙蛋白Ⅰ
文章编号:1000-2057(2005)06-0412-02
收稿时间:09 2 2005 12:00AM
修稿时间:2005年9月2日

Value of Measuring Thrombus Precursor Protein and Cardiac Troponin I in Patients with Chest Pain
YU Xiaohong, WEI Meifang, WU Xiang, et al.Value of Measuring Thrombus Precursor Protein and Cardiac Troponin I in Patients with Chest Pain[J].ACTA Academiae Medicinae Nantong,2005,25(6):412-413.
Authors:YU Xiaohong  WEI Meifang  WU Xiang  
Institution:Affiliated Hospital of Nantong University, Nantong 226001
Abstract:Objective:To investigate the values of measuring cardiac troponin I(cTnI) and thrombus precursor protein(TpP) in patients with chest pain.Methods:TpP and cTnI were measured in 106 patients with chest pain (36 patients with acute mycardial infarction,38 patients with unstable angina and 32 patients with non-coronary heart disease).Results:The concentrations of TpP were significantly higher in patients with acute mycardial infarction than in patients with unstable angina and in the control group(P<0.01).The cTnI positive rate was also significantly higher in patients with acute mycardial infarction than in patients with unstable angina(P<0.01) and in the control group(P<0.01).Conclusion::TpP and cTnI can be used as valuable paramteter for differential diagnosis of acute chest pain.
Keywords:Acute mycardial infarction  Unstable angina  Thrombus precursor protein  Cardiac troponin I
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