焦虑和抑郁障碍共病的血脂水平研究

目的　探讨血脂与焦虑和抑郁障碍共病的关系。方法　采用酶法检测焦虑和抑郁障碍共病 2 5例、30例重性抑郁症、2 0例焦虑症患者和 4 0例正常人的血清总胆固醇 (CHO)、甘油三酯 (TG)、高密度脂蛋白—胆固醇(HDL C)和低密度脂蛋白—胆固醇 (LDL C)。结果　共病组患者的血CHO浓度显著高于抑郁组、焦虑组和正常对照组 ;共病组的血TG浓度显著高于抑郁组和正常对照组 ,与焦虑组无显著性差异 ;共病患者的血HDL C浓度显著低于正常对照组 ,与抑郁组和焦虑组无显著性差异 ;共病组的血LDL C浓度显著高于抑郁组、焦虑组和正常对照组。结论　焦虑和抑郁障碍共病存在更严重的血脂代谢异常

Serum lipid concentrations in patients with comorbid anxiety and depression

Objective To explore the relationship between comorbid anxiety and depression (CAD) and serum lipid concentrations. Methods Serum concentrations of total cholesterol(CHO), triglycerides(TG), high density lipoprotein cholesterol(HDL C) and low density lipoprotein cholesterol (LDL C) were measured in 25 patients with CAD (CAD group), 30 depression patients (DG group), 20 anxiety patients (AG group) and 40 normal controls (NC group) by enzymatic methods. Results The serum CHO concentration in CAD group were significantly higher than those in DG group, AG group, and NC group. The serum TG concentration in CAD group was significantly higher than those in DG gruop and NC group. The serum HDL C concentration in CAD group were significantly lower than in NC group, and no significantly differences was found between CAD group, DG group and AG group. The serum LDL C concentration in CAD group was significantly higher than ones in DG group, AG group, and NC group. Conclusions Serum lipid concentrations in patients with CAD had more severe abnormality.