| A Multicentre Comparative Clinical Study of Three Types of IUD（Eight：Year Follow up） |
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| 作者姓名： | 方可娟 陈俊康 何美丽 韩耀玲 吴明辉 范慧民 韩丽辉 张德玮 王振海 葛杏林 张兢玉 张欣远 钱丽娟 王葆英 饶惠玲 孙麦巧 邹素玉 邓仁爱 夏寿恺 刘锋 邓蜀华 景锦华 刘常荣 左诗慧 吴学浙 杜明昆 李文贤 杨邦元 |
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| 作者单位： | [1]ShanghaiInstituteofPlannedParenthoodResearchShanghai,200032 [10]AffitiatedHospitalofMedicalUniversityofShangdongProvince,200032 [11]FamilyPlanningInstituteofChongqing,200032 [12]FourthPeopleHospitalofChongqing,200032 [13]FamilyPlanningInstituteofHananProvince,200032 [14]ShanghaiFirstMaternity＆InfantHealthHospital,200032 [15]AffiliatedGyn.＆Obs.HospitalofShanghaiMedicalUniversity,200032 [16]XinghuaHospital,ShanghaiSecondMedicalUniversity [17]ShanghaiInternationalPeaceMaternity＆ChildHeahhHospital,ShanghaiSecondMedicalUniversity [2]BeijingGynecological＆ObstetricalHospital,ShanghaiSecondMedicalUniversity [3]ShanghaiFamily,PlanningCommission [4]SecondHospital,MedicalUniversityofHebeiProvince [5]BeijingDongSiGynecological＆ObstetricalHospital,MedicalUniversityofHebeiProvince [6]SecondHospital,TianjinMedicalCollege [7]Maternity＆ChildHealthHospitalofShanxiProvince,TianjinMedicalCollege [8]Xi-AnForthHospital,TianjinMedicalCollege [9]QingdaoMaternity＆ChildHealthHospital,TianjinMedicalCollege |
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| 摘 要： | The Stainless steel ring(SSR), VCu200 and TCu220C were in randomized comparison for eight years in a cohort of 4,490 subjects covering 16 centres in 9 provinces and municipalities. The follow-up rate at the end of the eithth year was 90.33%. The cumulative continuation rates were 47.06 per 100 women at the end of the eighth year for SSR,54.05 for VCu200 and 61.14 for TCu220C. The cumulative pregnancy rates for VCu200 and TCu220C were 10.35 and 8.94 per 100 women respectively, significantly lower than 24.14 for SSR. There were significant differences in eight-year expulsion rates among SSR(21.69%), VCu200(13.05%) and TCu220C(7.48%). The removal for bleeding and/or pain was the lowest in SSR; and no significant differences were found between VCu200 and TCu200C. but the rate ws getting higher in VCu200 at the end of the eighth year than in TCu220C. The discontinued use of lUD for desire to become pregnant in rural area was extremely higher than in urban area. The risk of pregnancy and expulsion was in association with the types of lUD in this study, age at insertion, previous use of IUD and pregnancy frequency prior to insertion. The risk of pregnancy and expulsion for VCu200 and TCu220C was significantly lower than that for SSR. Failure risks were associated with age at insertion, the types of IUD in this study and pregnancy frequency prior to insertion, and failure risk in SSR was still higher than in VCu200 and TCu220C at the end of the eighth year. The study revealed that TCu220C was of good long-term safe ty, efficacy, and acceptability.
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| 关 键 词： | 多中心比较法 SSR IUD VCu200 TCu220C 怀孕周期 |
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