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Pathologic Characterization of a Renin-Secreting Juxtaglomerular Cell Tumor in a Child and Review of the Pediatric Literature |
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| Authors: | Rakesh K. Abbi Melinda McVicar Saul Teichberg Lawrence Fish Ellen Kahn |
| Affiliation: | a New York Medical College and Department of Pathology, Westchester County Medical Center, Valhalla, New Yorkb Division of Pediatric Nephrology, North Shore University Hospital-Cornell University Medical College, Manhasset, New Yorkc Electron Microscopic Laboratory, Department of Pediatrics and Pathology, North Shore University Hospital-Cornell University Medical College, Manhasset, New Yorkd Department of Surgery, North Shore University Hospital-Cornell University Medical College, Manhasset, New Yorke Department of Pathology and Department of Pediatrics, North Shore University Hospital-Cornell University Medical College, Manhasset, New York |
| Abstract: | We describe a rare case of renal hypertension in a 15-year-old caused by juxtaglomerular cell tumor and compare our findings with those of 20 children reported in the literature. These tumors are usually encapsulated and composed microscopically of polyhedral cells with bland nuclei separated by fibrovascular septa. Characteristic renin granules can be demonstrated by Bowie's stain or electron microscopy. These tumors are benign. Pathologists should recognize the morphologic characteristics of these tumors when dealing with renin-producing neoplasia. |
| Keywords: | juxtaglomerular cell tumor hypertension renal tumors |
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