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检测CA125、CA153和CA72—4对卵巢癌诊断及疗效观察的临床价值
引用本文:张辉,韩波.检测CA125、CA153和CA72—4对卵巢癌诊断及疗效观察的临床价值[J].临床和实验医学杂志,2010,9(8):568-569.
作者姓名:张辉  韩波
作者单位:1. 内蒙古自治区赤峰市医院,内蒙古,赤峰,024000
2. 辽宁中医药大学附属医院,辽宁,沈阳,110032
摘    要:目的观察癌抗原125(CA125)、癌抗原153(CA153)、癌抗原72—4(CA72—4)对卵巢癌的诊断及疗效观察的价值。方法采用电发光法检测32例卵巢癌和21例妇科良性疾病患者血清中CA125、CA153和CA72—4水平。结果卵巢癌患者血清中CA125、CA153和CA72—4含量高于良性对照组,联合检测CA125和CA72—4特异性、敏感性优于单独检测及其它组合。卵巢癌患者治疗后CA125、CA153和CA72—4降低(P〈0.05~0.01)。结论联合检测CA125和CA72—4对卵巢癌的诊断有重要的临床价值,弥补了单独检测CA125的不足。

关 键 词:卵巢癌CA125  CA153  CA72—4

Significance of serum CA125,CA153 and CA72-4 in diagnosis and therapeutic response of ovarian carcinoma
ZHANG Hui,HAN Bo.Significance of serum CA125,CA153 and CA72-4 in diagnosis and therapeutic response of ovarian carcinoma[J].Journal of Clinical and Experimental Medicine,2010,9(8):568-569.
Authors:ZHANG Hui  HAN Bo
Institution:ZHANG Hui1,HAN Bo2.The Hospital of Chifeng,Chifeng,Inner Mongolia 024000,China,2 The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang Liaoning 110032
Abstract:Objective To explore the significance of serum CA125,CA153 and CA72-4 in diagnosis and therapeutic response of ovarian carcinoma.Methods Serum levels of CA125,CA153 and CA724 were detected by electrochemical method.Results Serum levels of CA125,CA153 and CA72-4 were notably increased in patients with ovarian carcinoma in comparison with those of benign controls(P<0.01).The specificity and sensitivity of combined examination of serum CA125 and CA72-4 were much better than individual detection and other combi...
Keywords:CA125  CA153  CA72-4
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