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电针对脑出血大鼠脑组织病理形态学及脑组织含水量和神经损伤积分值的影响
引用本文:戴高中,陈跃来,顾法隆.电针对脑出血大鼠脑组织病理形态学及脑组织含水量和神经损伤积分值的影响[J].中国中西医结合杂志,2002,22(2):133-135.
作者姓名:戴高中  陈跃来  顾法隆
作者单位:戴高中(上海中医药大学附属龙华医院,上海,200032;江苏南通医学院附属医院中医科工作,江苏,226000)       陈跃来(上海中医药大学附属岳阳医院)       顾法隆(上海中医药大学附属龙华医院,上海,200032)       陈汝兴(上海中医药大学附属龙华医院,上海,200032)
基金项目:国家自然科学基金重点项目(No.39732510)
摘    要:目的:观察电针对大鼠脑出血模型的疗效。方法:选择胶原酶加肝素联合注射法诱导脑出血大鼠模型,观察电针不同穴位对其脑组织病理形态学、脑含水量和神经损伤积分值的影响。结果:电针水沟组(取水沟、上星穴)、电针风府组(取风府、哑门穴)均可明显改善胶原酶加肝素联合注射法诱导大鼠脑出血模型的脑组织形态学损害和神经行为功能的缺损,降低因出血导致的血肿周围组织的水肿;且电针水沟组在改善大鼠脑出血模型的脑组织形态学损害和神经行为功能的缺损方面(72h姿势反射和平衡反射积分值)优于电针风府组。结论:电针水沟、上星和电针风府、哑门对大鼠脑出血损伤均有一定程度的保护作用,且前者的保护作用优于后者。

关 键 词:脑出血  电针  病理形态学  脑组织含水量  神经损伤积分值  动物实验
修稿时间:2001年7月6日

Effect of Electro-acupuncture on Pathology, Water Content in Brain Tis sue and Neurologic Function Defect Scoring in Rat Model of Idiopathic Cerebral H emorrhage
Authors:DAI Gao zhong  CHEN Yue lai and GU Fa long
Abstract:To observe the effect of electro acupuncture (EA) on rat model of idiopathic cerebral hemorrhage (ICH). Methods: ICH rat model was established by collagenase and hepa rin injection to caudate nucleus and the effect of EA on pathology and water con tent in the brain tissue as well as the neurologic function defect scoring (NFD S) were observed. Results: In the Shuigou group (ICH rat model treated with EA a t Shuigou point and Shangxing point) and the Fengfu group (ICH rat model treated with EA at Fengfu point and Yamen point), the morphologic changes of brain and NFDS were improved and the edema in brain tissue around the hematoma was reduced after EA. The effect in the Shuigou group was superior to that in Fengfu group in improving morphological damage of brain and NFDS. Conclusion: EA can improve the brain injury of ICH in model ra ts.
Keywords:cerebral hemorrhage  electro  acupuncture  path o  morphology  water content in brain tissue  neurologic function defect scoring
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