益气敛微汤联用贝那普利治疗早期糖尿病肾病的临床研究

目的：观察益气敛微汤联用贝那普利对早期糖尿病肾病的作用并探讨其机制。方法：将早期糖尿病肾病患者86例随机分成治疗组与对照组,每组43例,对照组给予糖尿病饮食、控制血糖等常规治疗,治疗组在常规治疗基础上加用益气敛微汤口服治疗,2组均以2周为1个疗程。观察2组治疗前后尿素氮、血肌酐、血脂、糖化血红蛋白、丙二醛、超氧化物歧化酶、CRP、24小时尿蛋白排泄率等指标的变化。结果：治疗组治疗后除尿素氮、血肌酐、糖化血红蛋白外其他各项指标与治疗前比较均有明显改善（P〈0.01）,作用明显优于对照组（P〈0.01）。结论：益气敛微汤、贝那普利两者合用有协同作用,治疗早期糖尿病肾病的疗效优于单用贝那普利。

Clinical Study on Early Diabetic Nephropathy Treated with Yiqi Lianwei Decoction Combining with Benazepril

Objective:Observing the effects of yiqi lianwei decoction combining with benazepril on early diabetic nephropathy and exploring the mechanism.Methods:86Cases with early diabetic nephropathy were divided into treatment and control groups,the control group was given the basic treatment methods such as diabetic diet and controlling blood glucose medicine,etc.the treatment group was given yiqi lianwei decoction to take on the basis of the above treatment methods,2weeks was one treatment course.The changes of in...