| 梅尼埃病耳蜗及前庭功能损害程度的相关性研究 |
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| 引用本文： | 张少杰,梁勇,刘小龙.梅尼埃病耳蜗及前庭功能损害程度的相关性研究[J].听力学及言语疾病杂志,2011,19(1):17-21. |
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| 作者姓名： | 张少杰 梁勇 刘小龙 |
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| 作者单位： | 南方医科大学附属南方医院耳鼻咽喉科,广州,510515 |
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| 摘 要： | 目的探讨梅尼埃病耳蜗与前庭功能损害程度的相关性及不同程度病变的临床特征。方法对符合诊断标准的44例梅尼埃病患者进行纯音测听、畸变产物耳声发射、Metz重振试验、听性脑干反应(ABR)、耳蜗电图(ECochG)、甘油试验等听力学检查及双温试验、Fukuda踏步试验等前庭功能检查。将测试结果用耳蜗与前庭功能损害的综合评价函数进行评价,同时根据0.5、1、2kHz平均听阈,将病例分成I组6例(平均听阈<25dBHL)、Ⅱ组13例(平均听阈25～40dBHL)、Ⅲ组25例(平均听阈41～70dBHL)。结果Ⅰ、Ⅱ、Ⅲ组-SP/AP阳性率和CP异常率呈上升趋势,各组间差异有统计学意义(P<0.05)。半规管功能异常者(25例)中纯音听阈值、-SP/AP值和耳蜗电图阳性率明显高于半规管功能正常者(19例)(P<0.05)。ECochG阳性者(28例)Metz重振试验、甘油试验阳性率显著高于ECochG阴性者(16例)(P<0.05)。耳蜗功能损害的综合评价函数为f1=0.212Ⅹ11+0.259Ⅹ12+0.429Ⅹ13+0.367Ⅹ14,前庭功能损害的综合评价函数为f2=0.275Ⅹ21+0.375Ⅹ22+0.398Ⅹ23+0.119Ⅹ24,综合评价函数f1与f2呈正相关性(r=0.395,P<0.05)。结论梅尼埃病耳蜗功能与前庭功能损害程度呈较弱正相关性,运用主成分分析法构建的综合评价模型可以较全面综合原始变量信息,合理反映耳蜗和前庭功能损伤程度,为疾病诊断、治疗选择和疗效评价提供依据。
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| 关 键 词： | 梅尼埃病 耳蜗功能 前庭功能 |
Correlation Between Cochlear and Vestibular Dysfunction in Meniere's Disease |
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| Zhang Shaojie,Liang Yong,Liu Xiaolong.Correlation Between Cochlear and Vestibular Dysfunction in Meniere's Disease[J].Journal of Audiology and Speech Pathology,2011,19(1):17-21. |
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| Authors: | Zhang Shaojie Liang Yong Liu Xiaolong |
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| Institution: | Zhang Shaojie,Liang Yong,Liu Xiaolong(Department of Otorhinolaryngology-Head and Neck Surgery,Nanfang Hospital,Southern Medical University,Guangzhou,510515,China) |
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| Abstract: | Objective To investigate the correlations between the cochlear and vestibular dysfunctions and to study the clinical features of different pathological changes in Meniere's disease.Methods 44 patients diagnosed as Meniere's disease according to the 2006 Guiyang Diagnosis Standard received audiologic and vestibular assessments,including pure tone audiometry,distortion product otoacoustic emission(DPOAE),auditory brainstem response(ABR),electrocochleography(EcochG),Metz s recruitment test,the glycerol test,ve... |
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| Keywords: | Meniere's disease Cochlear function Vestibular function |
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