| 盐酸戊乙奎醚对胃解痉作用的药效学研究 |
| |
| 引用本文： | 刘诣,莫正纪,陈淑杰,郭熹. 盐酸戊乙奎醚对胃解痉作用的药效学研究[J]. 中国医药工业杂志, 2003, 34(9): 453-455,475 |
| |
| 作者姓名： | 刘诣 莫正纪 陈淑杰 郭熹 |
| |
| 作者单位： | 四川大学华西药学院药理教研室,四川成都,610041 |
| |
| 摘 要： | 研究盐酸戊乙奎醚(PQN)肌肉注射及灌胃给药对麻醉及清醒家兔在体胃及豚鼠离体胃条的抑制收缩作用。结果表明，PQN能抑制由乙酰胆碱(Ach)和氯贝胆碱引起的胃内压上升，拮抗Ach对离体胃条的收缩作用，并能抑制离体胃条的自主收缩。
|
| 关 键 词： | 盐酸戊乙奎醚 解痉作用 药效学 |
| 文章编号： | 1001-8255(2003)09-0453-03 |
Effects of Penequinine Hydrochloride on Gastric Spasm |
| |
| LIU Yi,MO Zheng-Ji,CHEN Shu-Jie,GUO Xi. Effects of Penequinine Hydrochloride on Gastric Spasm[J]. , 2003, 34(9): 453-455,475 |
| |
| Authors: | LIU Yi MO Zheng-Ji CHEN Shu-Jie GUO Xi |
| |
| Abstract: | The effects of penequinine hydrochlordie (PQN) im or ig on stomach in anaesthetic or conscious rabbits and the stomach strips isolated from guinea pigs were investigated. The results showed that PQN could inhibit the increase of pressure in stomach caused by acetylcholine (Ach) or bethanechol chloride, and antagonize contraction of stomach strip caused by Ach, it also could inhibit the independent contraction of stomach strip. |
| |
| Keywords: | penequinine hydrochloride anti-spasm pharmacodynamics |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
