2002-2011年温州某医院住院病人甲状腺相关疾病谱分析

目的了解实施全民食盐加碘后，近10年温州某院甲状腺相关疾病住院病人疾病谱，为临床防治甲状腺疾病提供科学依据。方法收集该院2002--2011年甲状腺相关疾病的住院病人2130例病案，采用ICD一10对出院病案主要诊断进行疾病分类，采用SPSS16．0进行统计分析。结果2002--2011年甲状腺相关疾病占出院病人总数的1．04％，其男女之比为1：4．21，高发年龄是15—44岁，占总数的44．88％。在所有甲状腺相关疾病中其他非毒性甲状腺肿（E04）最多，占总数的46．34％，其他的依次为甲状腺良性肿瘤（D34）18．12％、甲状腺恶性肿瘤（C73）17．60％、甲状腺毒症（E05）9．20％、甲状腺炎（E06）3．43％、妊娠合并甲状腺疾病（099．2）3．29％、其他甲状腺功能减退症（E03）1．92％、其他甲状腺疾病（E07）0．09％。先天性碘缺乏综合征（E00）、碘缺乏相关性甲状腺疾患和有关情况（E01）、临床症状不明显的碘缺乏性甲状腺功能减退症（E02）都为0。甲状腺恶性肿瘤以乳头状癌最多，占恶性肿瘤的91．74％，其余滤泡性腺癌占总数1．60％，髓性癌占总数1．07％，未分化癌占总数0．27％，其他癌占总数5．34％。结论收集的病例数多，病种多样，可以为临床研究足量、超足量以及过量碘摄入后的甲状腺疾病提供有价值的参考资料。

Analysis of thyroid disease spectrum of resident patients in a hospital of Wenzhou city during the period 2002--2011

Objective To investigate thyroid disease spectrum of inpatients of a hospital in Wenzhou City in the last decade after universal salt iodination and provide scientific basis for clinical prevention and treatment. Methods The cases of thyroid disease were collected in the hospital from 2002 to 2011. The classification and coding of these cases＇ discharged diagno- sis was according to the ICD-10 and analyzed by SPSS 16.0 software package. Results The 2 130 cases of thyroid disease were about 1.04% of whole inpatients during the last decade. The ratio of male to female was 1 to 4.21. The incidence was highest between the ages of 15 and 44, occupying 44.88% of whole inpatients. Among all the thyroid disease, the nontoxic goiter（E04） was highest（40.71% ）, then was Benign neoplasm of thyroid gland （D34） （18.12%）, Malignant neoplasm of thyroid gland （ C73 ） （ 17.60% ）, Thyrotoxicosis （ E05 ） （9.20%）, Thyroiditis （ E06 ） （ 3.43% ）, thyroid disease complicating pregnancy , childbirth and the puerperium （099.2） （3.29%） , other hypothyroidism （ E03 ） （ 1.92% ） and other disorders of thyroid（E07） （0.09%） in order. Congenital iodine-deficiency syndrome （E00）, iodine-deficiency-related thyroid disorders and allied conditions （E01）, Subclinical iodine-deficiency hypothyroidism（E02） all were 0%. Among Malignant neoplasm of thyroid gland, Papillary carcinoma occupies first place , which was 91.74%, then was Follicular adenocarcinom（ 1. 60% ）, Medullary carcinoma （ 1.07% ） and Anaplastic carcinoma （0.27%） in order, and other Carcinoma was 5.34%. Conclusion The cases can provide valued reference materials for the clinical study of thyroid disease patients that take different iodine.