保山市1989～2011年HIV感染者AIDS病人死亡情况分析

目的 分析1989～2011年保山市HIV感染者AIDS病人死亡情况,为该人群的管理和治疗提供科学依据.方法 2012年8月1日从中国CDC信息系统艾滋病综合防治信息系统中的“历史卡片下载”处下载至2011年年底的HIV感染者AIDS病人历史数据库.应用描述性流行病学方法对HIV/AIDS患者的一般人口学特征,死亡病例的生存时间、CD4、死亡原因等进行分析.结果 1989～2011年保山市共报告HIV感染者及AIDS病人4 562例,其中死亡883例,死亡率为19.36％.在死亡患者中男性占71.0％,21～40岁的占62.2％,已婚有配偶者占61.0％,初中及以下文化者占68.7％,汉族占77.1％,农民占73.6％,异性传播占59.6％;HIV感染者占50.4％,AIDS病人占49.6％;HIV/AIDS患者的中位生存期为5个月,在确证后1个月内死亡的占26.3％,一年及以上死亡者占35.1％；CD4≤50、51≤CD4≤100、101≤CD4≤200、201≤CD4≤350、CD4≥351者生存时间≥1年的分别占29.8％,44.8％,46.0％,70.8％,65.5％；在HIV感染者中感染途径为异性传播的占51.2％,异性传播在AIDS病人中占68.0％；主要死亡原因为艾滋病相关性疾病,占73.6％.结论 保山市既往报告死亡的HIV感染者及AIDS病人以汉族、已婚文化程度较低的男性青壮年农民为主,其感染途径主要为异性接触传播；CD4计数越高,其生存期越长；AIDS相关性疾病是导致HIV/AIDS患者死亡的主要原因.

Analysis of HIV/AIDS cases and dead cases from1989 to 2011 in Baoshan Prefecture

Objective To understand the specific status of HIV/AIDS cases and dead cases in Baoshan prefecture from 1989 to 2011.Methods The accumulative data of HIV/AIDS cases within 23 years in Baoshan prefecture were downloaded from China information system for diseases control and prevention.A total of 4 562 cases including 883 dead cases were report ed from 1989 to 2011.Results Of the 883 dead cases,71.0% of them were males and 62.2% were aged between 21-40 years.Most were Han ethnicity（77.1%）,married（61.0%）,and had less than at least a junior high school education（68.7%）,farmers accounted for 73.6% and 59.6% of them were infected by heterosexual contact.HIV and AIDS cases accounted for 50.4% and 49.6%,respectively.The median survival periods after confirmed HIV inectioin were 5 months,26.3% of cases died within one month and 35% were dead more than 12 months after confirmed HIV infection.Those with CD4≤50,51≤CD4≤100,101≤CD4≤200,201≤CD4≤350,CD4≥351 jaad a survival duration of more than 1 year accounted for 29.8%,44.8%,46.0%,70.8%,65.5%,respectively.HIV and AIDS cases had a heterosexual contact occupied 51.2% and 68.0%,respectively.The dead cases died of AIDS-related disease accounted for 73.6%.Conclusion The accumulatively reported dead HIV/AIDS cases were mainly infected through heterosexual contact,and the higher CD4 counts is,the longer survival duration would be.The death was mainly due toAIDS-related diseases.