正负性情绪图片编码加工功能磁共振成像研究

目的 探讨正负性情绪图片加工所涉及的相关神经机制. 资料与方法 对20名健康自愿者(男女各10名,年龄20～25岁,视觉呈现彩色负性、正性、中性情景图片)行功能磁共振成像扫描并进行后处理. 结果 与中性图片加工相比,正负情绪激活杏仁核、前额叶不同亚区、扣带回、颞中回、颞上回等共同脑区.负性图片显著激活双侧杏仁核、右侧前额叶眶回、左侧海马、丘脑和梭状回等脑区;正性图片激活右侧杏仁核、左侧前额叶背侧和右侧海马等脑区. 结论 正负性情绪加工涉及共同的和相对特异的神经机制.前额叶和杏仁核等是情绪加工中的重要结构,前额叶参与情绪加工符合情绪效价假设.

Functional MRI Study of Encoding Processes of Positive and Negative Emotional Pictures

Objective To explore the corresponding neural mechanisms involved in the process of the positive and the negative emotional pictures.Materials and Methods 20 normal subjects participated in the study,viewing the color episodic pictures including positive,negative and neutral pictures while functional MRI scans were performed and postprocessing of the functional data was completed.Results Compared with the neutral pictures,the emotional picture processes involved various brain regions including the amygdala,prefrontal cortex,middle and superior temporal gyrus and anterior cingulate gyrus,etc..The negative pictures activated the brain regions including the bilateral amygdala,right orbital gyrus,left hippocampus,thalamus and fusiform gyrus,etc.,while the positive evoked the right amygdala,left dorsal prefrontal cortex and right hippocampus,etc.Conclusion The positive and negative emotional encoding processes involved in common and relatively specific neural mechanisms.Amygdala and various prefrontal subcortex were the important structures in the different emotional picture processes.Participation of prefrontal lobe in emotional processing was consistent with emotional valence hypothesis.