Evaluation of two real-time PCR chemistries for the detection of Chlamydophila pneumoniae in clinical specimens |
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Authors: | Stephanie L. Mitchell Sona Budhiraja Kathleen A. Thurman W. Lanier Thacker Jonas M. Winchell |
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Affiliation: | aRespiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA;bMolecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA |
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Abstract: | Chlamydophila pneumoniae is an atypical bacterial respiratory pathogen that is responsible for 3–10% of community-acquired pneumonia cases. We report the evaluation of two distinct real-time PCR assays for rapid and specific detection of C. pneumoniae. We tested 401 clinical specimens, finding 5.7% positive, and confirmed a localized outbreak. |
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Keywords: | C. pneumoniae Real-time PCR Community-acquired pneumonia CAP TaqMan LUX |
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