| 冠心病患者免疫反应的变化研究 |
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| 引用本文： | 刘年凤. 冠心病患者免疫反应的变化研究[J]. 赣南医学院学报, 2003, 23(3): 274-276 |
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| 作者姓名： | 刘年凤 |
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| 作者单位： | 江西上饶市人民医院,江西,上饶,343000 |
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| 摘 要： | 目的 :探讨免疫反应在冠心病中的作用。方法 :5 8例患者经冠状动脉造影后分为 4组 :心肌梗塞 (AMI)组 15例、不稳定性心绞痛 (UAP)组 10例、稳定性心绞痛 (SAP)组 11例与冠脉造影正常的对照组 2 2例 ,测定血清免疫球蛋白IgG、IgA、IgM和补体C3、C4 的水平。结果 :AMI组的IgG、IgA、补体C3、C4 的水平明显高于SAP组和对照组 (P <0 .0 5 ) ;UAP组的IgG和C3水平也明显高于SAP组和对照组 (P <0 .0 5 ) ;SAP组与对照组之间IgG、IgA、补体C3、C4 的水平及各组间IgM水平比较无显著性差异 (P >0 .0 5 )。结论 :IgG、IgA、C3、C4 的水平增高与冠心病有一定的联系 ,免疫反应可能是促进冠心病的形成与进展的重要因素
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| 关 键 词： | 冠心病 免疫反应 免疫球蛋白IgG、IgA，IgM，补体C3，C4 |
| 文章编号： | 1001-5779(2003)03-0274-03 |
| 修稿时间： | 2002-11-07 |
A Study of the Change of Immunoreaction in Patients With Coronary Heart Disease |
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| LIU Nian feng. A Study of the Change of Immunoreaction in Patients With Coronary Heart Disease[J]. Journal of Gannan Medical College, 2003, 23(3): 274-276 |
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| Authors: | LIU Nian feng |
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| Affiliation: | LIU Nian feng |
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| Abstract: | Objective:To study the relationship between immunoreaction and coronary heart disease(CHD).Methods:The levels of immunoglobulin(IgG?IgA?IgM)and complement(C 3?C 4)were measured in 58 patients given angiography,the patients were divided into 4 groups:15 cases of myocardial infarction(AMI);10 cases of unstable angina pectoris(UAP);11 cases of stable angina pectoris(SAP)and 22 cases of normal control.Results:The levels of IgG?IgA?and C 4 in AMI group and the level of IgG and C 3 were significantly higher than those in SAP and control groups.While the levels of IgG?IgA?and C 4 between SAP and control groups,the levels of IgM in all groups showed no significant difference.Conclusion:The incidence of CHD is correlated with the elevation of IgG?IgA?C 3 and C 4.and the immunoreaction may participate in the generation and progress of CHD. |
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| Keywords: | CHD immunoreaction immunoglobulin(IgG IgA IgM)complement(C 3 C 4) |
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