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冠心病患者免疫反应的变化研究
引用本文:刘年凤.冠心病患者免疫反应的变化研究[J].赣南医学院学报,2003,23(3):274-276.
作者姓名:刘年凤
作者单位:江西上饶市人民医院,江西,上饶,343000
摘    要:目的 :探讨免疫反应在冠心病中的作用。方法 :5 8例患者经冠状动脉造影后分为 4组 :心肌梗塞 (AMI)组 15例、不稳定性心绞痛 (UAP)组 10例、稳定性心绞痛 (SAP)组 11例与冠脉造影正常的对照组 2 2例 ,测定血清免疫球蛋白IgG、IgA、IgM和补体C3、C4 的水平。结果 :AMI组的IgG、IgA、补体C3、C4 的水平明显高于SAP组和对照组 (P <0 .0 5 ) ;UAP组的IgG和C3水平也明显高于SAP组和对照组 (P <0 .0 5 ) ;SAP组与对照组之间IgG、IgA、补体C3、C4 的水平及各组间IgM水平比较无显著性差异 (P >0 .0 5 )。结论 :IgG、IgA、C3、C4 的水平增高与冠心病有一定的联系 ,免疫反应可能是促进冠心病的形成与进展的重要因素

关 键 词:冠心病  免疫反应  免疫球蛋白IgG、IgA,IgM,补体C3,C4
文章编号:1001-5779(2003)03-0274-03
修稿时间:2002年11月7日

A Study of the Change of Immunoreaction in Patients With Coronary Heart Disease
LIU Nian,feng.A Study of the Change of Immunoreaction in Patients With Coronary Heart Disease[J].Journal of Gannan Medical College,2003,23(3):274-276.
Authors:LIU Nian  feng
Institution:LIU Nian feng
Abstract:Objective:To study the relationship between immunoreaction and coronary heart disease(CHD).Methods:The levels of immunoglobulin(IgG?IgA?IgM)and complement(C 3?C 4)were measured in 58 patients given angiography,the patients were divided into 4 groups:15 cases of myocardial infarction(AMI);10 cases of unstable angina pectoris(UAP);11 cases of stable angina pectoris(SAP)and 22 cases of normal control.Results:The levels of IgG?IgA?and C 4 in AMI group and the level of IgG and C 3 were significantly higher than those in SAP and control groups.While the levels of IgG?IgA?and C 4 between SAP and control groups,the levels of IgM in all groups showed no significant difference.Conclusion:The incidence of CHD is correlated with the elevation of IgG?IgA?C 3 and C 4.and the immunoreaction may participate in the generation and progress of CHD.
Keywords:CHD  immunoreaction  immunoglobulin(IgG  IgA  IgM)complement(C  3  C  4)
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