Factors determining successful outcome following pneumatic balloon dilation in achalasia cardia. |
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Authors: | Rajiv Mehta Anil John Shine Sadasivan C P Mustafa R Nandkumar V V Raj V Balakrishnan |
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Institution: | Department of Gastroenterology, Amrita Institute of Medical Sciences,Amrita Lane, Elamakkara P O, Cochin 682 026, India. rmgastro@yahoo.com |
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Abstract: | BACKGROUND: Pneumatic balloon dilation is a popular method of treating patients with achalasia cardia. It may be useful to know the factors that predict response to this treatment. AIM: To determine predictors of outcome following pneumatic balloon dilation in patients with achalasia cardia. METHODS: Records of 62 patients who had undergone pneumatic dilation using Rigiflex balloon dilators (Boston Scientific, Boston, MA, USA) were reviewed. Follow-up data were available for 52 patients. Data from patients with and without improvement in symptoms were compared. RESULTS: Of the 52 patients (age mean 44 range 11-68] years; 27 male; median symptom duration 20 4-90] months], 42 (81%) patients had response in symptoms after balloon dilatation. On univariate analysis, the responders more often had age> 40 years (26/42 62%] versus 1/10 10%], p=0.003), and less often had lower esophageal sphincter pressure> 50 mmHg (8/10 80%] versus 10/42 24%], p=0.0007) and mid-esophageal body hypocontraction (7/10 70%] versus 12/24 29%] p=0.01) than the non-responders. On multivariate analysis only age
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