A novel bromolactonization reaction using racemic 3-bromo-5-isobutyl-5-methylhydantoin |
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Authors: | Youn-sang Cho Sang-sup Jew You-sup Chung |
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Affiliation: | 1. College of Pharmacy, Seoul National University, 151, Seoul, Korea
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Abstract: | By using racemic 3-bromo-5-isobutyl-5-methylhydantoin (3a′) in dry N, N-dimethylformanide which is a model reagent for asymmetric bromolactonization, bromolactonization of a series of olefinic acids was carried out to furnish corresponding bromolactones in moderate yields. |
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